Session Chair: Julie Schappler
Keynote Speaker: Pavel Kuban, Institute of analytical Chemistry of the Czech Academy of Sciences, Brno, Czech Republic
Where it all begins!
Sample preparation is the first stage of the bioanalytical process and is applied to clean-up and/or enrich the sample before analysis to improve its detection without fouling the analytical device. According to the nature, availability, volume, and stability of the sample, as well as the goal of the analysis (i.e., targeted or untargeted) and other constraints (e.g. throughput, cost), different sample preparation should be used. The choice of this analytical step is very important, since depending on the option selected, sample identification and quantification may be affected, and results biased. All these considerations apply regardless of the field of applications, either in drug development studies, pharmacological, toxicological, and forensic analyses, clinical biochemistry assays, or in omics fields.
Nowadays, there is a growing interest in miniaturized sample preparation approaches, which may be used in the case of minute amounts of scarce matrices (e.g. lachrymal fluid, cerebrospinal fluid, saliva). In this context, the keynote speaker of this session will explain why and how liquid-phase microextractions are real alternatives to conventional sample preparations approaches in bioanalysis.
Oral and poster submissions on the topic of “Sample preparation” should include original approaches to address sample preparation issues encountered in the different fields of bioanalysis.