Session Chair: Norberto Guzman
Keynote Speaker: Kiyohito Shimura, School of Medicine, Fukushima Medical University, Fukushima, Japan
Biointeractions and affinity separation in the life sciences
Effective determination of small molecules and biomolecules in complex matrices often requires methods that are accurate, rapid, inexpensive, easy to perform, and ease of result interpretation. In many instances, immunoassay methods offer these advantages. Several immunochemical methods have demonstrated important applications for use in the life sciences, clinical diagnostic, and in various enterprises such as the food and pharmaceutical industries. The development of high-sensitivity immunoassays has evolved considerably in the last decade and has enabled the improvement of high-throughput assays for multiple applications.
Today, the field of affinity interactions that include the use of antibodies, lectins, aptamers and other affinity ligands play a prominent role in the analysis of a wide range of analytes. As a particular note is the merging of affinity-capture assays with analytical separation instruments coupled to powerful detectors, such as laser-induced fluorescence and mass spectrometry, which is becoming of great value for the discovery of new biomarkers aimed at disease diagnosis. The merging of these technologies also plays a significant role in the development of platform strategies for drug discovery and quality control of small molecule drugs and biomolecules, such as monoclonal antibodies and vaccines.
This session will highlight the most common types of biointeractions and affinity separation in the life sciences focusing in the advancements of immunoaffinity capillary electrophoresis to stay current with state-of-the art bioanalytical technologies.